One per series, like usual. Anime ONLY! If I was including non-anime fights, then Answer would no question be number 1. There is no Fate/Stay Night anime. I guess this “Links and runner ups” is a series now. Kewl.
Runner-Up: Saitama vs. The Sea King/Genos/Underground King
Runner-Up: Polnareff vs. Vanilla Ice/CenterFold, Jotaro vs. D’Arby/D’Arby, Iggy vs. Petshop
Runner-Up: Shiki vs. Zombies/Fujino/Souren/I mean, the whole damn film series really.
Runner-Up: Okay, here we go... Naruto vs. Pein/Sasuke/Madara/Haku/Neji/Gaara, Sasuke vs. Gaara/Haku/Naruto/Madara/Orochimaru, Kakashi vs. Zabuza/Obito/Haku/Pein, Rock Lee vs. Gaara. Did I get them all?
Runner-Up: Luffy vs. Arlong/Crocodille/Eneru/Aokiji/Lucci/Magellan/Dofflamingo, Zoro vs. Mihawk/Mr.1/Kuma/Kaku, Akainu vs. Whitebeard. Couldn’t resist linking my video, because why not?
Runner-Up: Gon vs. Genthru/Hisoka, Killua vs. Youpi/Sabu/OrthoTwins, Kurapika vs. Uvogin, Netero vs. Meruem.
Runner-Up: The whole film. All of it.
Actual Entry: Shichika vs. Emonzaemon
Runner-Up: Mustang vs. Envy/Lust